It depends, if money is not a problem, have George Anderson & team build you a Shelby engine. I think they build the majority of these engines. He's also a Shelby continuation series dealer.
If not, build a Genesis 427. I'm building 527 iron block from them. I did get a great deal with a Shelby timing cover and water pump, I guess them and the side oiler, are my,.....bragging rights.