I used weather tight where the application called for it and if .25 spade connectors were avaialble, I used the best grade connector I could get.
Each connection was crimped and then soldered. Each connector was shrink-wrapped. Harnesses were cable tied until it became 3/8 inch, then a heavy plastic wrap was used to protect teh wiring from vibration and wear.
I used color coding as best I could, with the wire I was using. Most was 16 guage, but there were a few 18 guage wires for signals.
Tach and speedo were shielded wires with grounded mesh as a wrap.
I used a 1 - 2 inch service loop for most of the wiring and screwed down anchores to secure the harnesses.
I have not had electrical problems other than LED lights ( not enough load ).