You can have your cake and eat it too....
The short deck mod blocks will go to about 5.3L, and 400 hp is pretty easy with a 2V, 3V, or especially a 4V head. Aftermarket cams will give you a real lope. Still EFI...
Working on a 327 modular engine right now that should be a good bit over 500hp, naturally aspirated....pump gas...EFI.
However, one thing that a lot of guys aren't considering is the cost of the Coyote, the cost of the ECU/harness, and the extreme cost of a supercharger if you want more than 400hp. In addition, the cost of adapting the Coyote to the car is another chunk of change.
Not sure what the appeal is.....is it gas mileage? Just the fact that it's new technology? Something different?
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There are known issues with the cam phasers on the 3V and Coyote engines. Don't think that Ford Racing will come and work on the engine for you in your own garage.
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