[DanEC]

It's become such a common practice for over 40 years now that I think any major problems would have long ago surfaced. I based that on the L88 Chevy but I believe Ford produced a few aluminum heads in the 60s also. There are some adjustments that have to be made - I have to adjust the solid lifter valves on my aluminum head 427 66 Corvette differently due to different expansion coefficients. Occassionally you will hear about a head gasket failure - but that goes for iron head motors also.