Is it real? We all know what they mean so unless you're driving a 60's original, best answer="No"
If the person seems genuinely interested, I'll say it's a replica. Some go on to ask which brand and the conversation goes from there. Most here in the Caribbean ask what kind of car it is or how old. One guy who sees it on a semi regular basis always yells "Aston Martin!" when I drive past.
Occasionally they yell "Shelby" or "Cobra" and most who have no clue what it is are just amazed that it has a V8.
One afternoon in the parking lot of the local marina, as I negotiated a speed bump by the taxi stand this huge guy left his domino game, hurried over and asked gruffly, "I heard you built that car yourself - Is that true?" I just smiled and nodded. Right after that I passed a group of what appeared to be Aussies on an open top tour jeep and one guy leaned way over and said "you've got to be sh-ttin' me!" I suppose that was about the last thing he expected to see on the road down here.