Coyote engines are wide, wider than FEs and 385 big blocks. Yes, they're the 'latest and greatest' from Ford, and probably the easiest with which to pass emissions tests, but they will pose other challenges.
If I was building a car today I'd be inclined to go with a 427W SBF, most likely fuel injected. Relatively narrow configuration, good torque and the benefits of fuel injection. Whether you go with a 4 barrel throttle body configuration or an 8 stack setup is up to personal preference and budget, but either will work and look darn fine when you open the hood.
Here's a link to a Ford Performance crate engine rated at 450 horsepower and 520 lb-ft torque (
https://fordperformanceracingparts.c...KeyField=13509), but there are a number of engine builders who will build one specific to your configuration and what you're looking for.
Enjoy.