here is Mike Stenhouse's gearing calculator:
http://www.secondstrike.com/Technical/GearCalc.asp
I agree that one has to think carefully about the intended use and expectations of their Replica. I think a lot has to do with camming. Unless you are gearing for "racing", then most likely you will want some sort of reasonable cruise RPM. I have a stroked Windsor, and can comfortably cruise with all sorts of hill-climbing & passing torque at 1800-2000 RPM.
My car also slows in acceleration once i shift into my .68 Tremec's fifth gear, but since this is about 135 mph at @ 6000 RPM, it isn't something i experience on the "street." I am happy to have the relaxed cruise RPM i do.
Remember that more "power" is just a downshift away. In a "bigger block" engine, i would suggest gearing so one has about 2000 RPM at cruise (60-70 mph), and in a small block, ie, a 302 CI car, something more like 2500 rpm in fifth.