Put 4.09's (Jag rear) in my Unique, with XB-3 302 crate motor. Still a leftover from drag racing youth, I guess, but I can cruise with great comfort at any speed up to 60 in the first 4 gears - 60 in fourth is 3000 rpm. Have a 3550 w/.68 fifth gear and love it - 80 mph is about 2500 rpm.
Wheelspin nonexistant unless you drop the hammer; othewise just flat digs in and hauls a**. Very easy to bounce off the rev limiter in first (set @ 6200), it winds out so quick. I think most here would consider 4.10's useless...I think 3.23's are useless. 99,99% of all your street driving is up to or around 80-85 mph, and the acceleration factor with steeper gears has to be experienced to believe. 3.23's, 3.08's great if you think you'll spend lots of time up around 150-160 mph; don't have too many roads, around here anyway, that will permit that.
Mebbe that 351 will smoke the tires all the time with 4.10's - mebbe not. But I stone-cut, iron-clad guarantee you that NOBODY will outrun you in the stoplight drags.