John,
You are asking me for directions.... Wow, you must be over getting lost from the last ones.
From the Phoenix area it is about 4 hours give or take. Friday night Traffic will be nasty. If you do go through Phoenix you need to get off at the carefree highway and head west towards Wickenburg. Follow the signs from Wickenburg to Kingman and on to Laughlin. If you go to Flagstaff you add about 2 hours to your trip.
I think the I-10 through Quartsite takes a little longer but not sure.
I'll email you my Cell phone number just in case.
Mike