Ernie (Excaliber), can tell you all about how to increase your gas mileage from around 3 MPG to around 10 MPG. Above that and he may have to do some research. He still hasn't figured out how I get 29 MPG on the highway.
But all jokes aside, the 350 Chevys have never been really good gas mileage engines. I know several people who have tried many things and I don't know of many that have really gained a lot. But if it can be done I am sure some of these guys can help. Also maybe you could check on the Corvette or one of the Chevy clubs as they would certainly know all the tricks.
Ron