I'm meant the question to be more generic, but perhaps a "generic" answer is impossible given the variables for cam design!
But lets take what might be a typical application. 2600 pound car, 3.50 (or HIGHER) rear axle, top loader and FE (390-427-428), flat tappet, street use with a "lumpy" idle. In general would a dual pattern cam work better with this scenario than a single pattern? Lets use the more common medium riser, iron or alloy head.
I think most folks running a top loader seldom go below a 3.50 rear ratio (or wish they hadn't).
"Not Yet",,,,, but soon? Hows that Kirkham build coming along?