there are a number of items that should be checked.
1. rubber gaskets should be upgraded to something that will work with ethanol.
2. plastics used for floats in carbs needs to be upgraded or changed to brass.
3. fuel lines NOT rated for ethanol will need to be changed as the lining will peel apart ( This one was hard for me to believe ).
4. Fuel tank gaskets not rated for ethanol will leak.
5. fuel delivery systems may have a small problem with maintaining pressure.
I hadn't heard of the plugs in the holleys melting, but I think I will be switching back to the brass ones.