I'm a small block guy but since no one is jumping in here I'll try to get the ball rolling for you. The consensus I recieved when setting up for webers was that Webers do "not" run best on a split duration cam. I am, however, running a split duration cam for the reason that I didn't want to change out a fairly new cam which wasn't "really" radical to begin with. It seems to run pretty well. On my next motor I will switch to a single duration cam with a llittle more lift & a bit more duration.
I am running a Comp Cams "Nostalgia Plus Hydraulic"
I am looking at the Isky FL-368