Go due North from The City, cross the Golden Gate bridge and tour the Napa Sonoma "wine country" for a day or two. Continue North hugging the coast all the way to Oregon. Breathtaking scenery and some quaint little bed-and-breakfast towns for stops. The coast of Oregon is just as beautiful. Come back down thru Lake Shasta and then cut over to Redding and take hwy44 into the Northern Sierras. Go South to Tahoe and Yosemite. Or you could do the whole thing in reverse.
One thing though, last time, if you didn't do State route 1, from SF to Pismo beach, it's a "must do".
http://en.wikipedia.org/wiki/Califor...Redwood_Empire
jdog
P.S. Find a computer and do a post when you get to Tahoe, maybe one of us NorCal Cobra guy's will drive up and take you up on that free beer!