[Paul F]

On your way down 101, you'll run into Humbolt Redwoods State Park. Stop in Founders Grove. Tallest trees in the world. If you do that, skip Muir woods. I agree with Jamo and BobCowan. Skip the wine country (I live there). But do go all the way down hwy 1 and Shoreline highway back to 101. Just before the Golden Gate bridge, exit and take Conzelman Rd up a 1/2 mile or so for a fantastic view.

Carmel and 17 mile drive, some of the most fantastic coastline you will see. Yosemite is a must. If you make it to Reno, car museum.