[Jamo]

It will screw up valve stems and plays hell with pressure senders in modern cars.

With the low pressures we run in the Billboards, I can't see it as much of a problem when they have to break the bead...I don't leave it in there long enough (just to get home).

Assolutely a no-no with run-flats (course, you don't need it to limp home), as Goodyear and Chevy make plain in their literature.