I had a 425ci Windsor in mine the first time. Then I built a 428FE to replace it. There wasn't anything wrong with the Windsor, it actually made more torque than the FE, but I get bored easy and wanted to try something new.
I agree with these guys about horsepower to a certain point. In my eyes, you can have as much horsepower as you want, you don't have to drive it wide open all the time.
With that being said, there are drawbacks to large amounts of horsepower. But with a large cubic inch big block, you can have 500-600hp with street-easy driving characteristics.
Where you start having problems with horsepower is when you're trying to squeeze 500-600hp out of a 347, a 351, or something with low displacement. Then you have to start looking at really large head port volumes, large cam durations, and high compression.
You'll find that a lot of guys have large cubic inch FE's with 600hp or maybe a tad more...and they're completely streetable.
I had the very combination that you're talking about....428ci FE, aluminum heads, Tunnel Wedge intake, dual Demon carbs, etc. That engine dyno'd at 533hp and 472 lb-ft of torque. That engine was a just a hair over the top...it had 11:1 compression (but ran on 93 octane) and a large solid roller cam. And yes, the dual carbs are a pain in the butt sometimes.