I doubt either candidate will make an issue of their family connections. McCains wife has not been too outgoing about Kathleen Portalski.
I almost feel bad for candidates because somebody really feels the need to dig up this kind of stuff instead of focusing on what they will or won't do for the country.
In case I ever do something stupid and run for office - here it is - I have not talked to my mum in 3 years, and until my dad died last summer I had not talked to or seen my sister in 10. I also see no point in not inhaling. So who's gonna vote for me?