Neutral
I have used the lambda sensor to tune, and with the larger air corrector the mixture gets lean at the top end. The 100 worked best and the A/F ratio stays steady up to max rpm. I started with the 220 air corrector and went all the way down to 80, but I settled for the 100 which I have now. When I put the 115 on to double check that I am not going astray with the tuning I get a lean top end.
Webers were used on smaller engines when they were popular, and the formula may hold true for them.
I do not think running webers without the chokes will work. The chokes have a distinctive shape inside to create under-pressure for the aux venturis to work.
You con go larger with up to 45mm chokes for the 48IDA.
Top end will probably be some better but driveability will suffer.
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Nothing sounds better than a Cobra in a Tunnel !
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