if there is a datalogger for use with the thruster, that is the way to go.
the datalogger will have a seperate program for your computer called accel dfi datamap and you download off of the datalogger in the car to this program, then you can export this file to calmap and under datalogging-fuel you can bring it up and run it on your ve table that is in the car and it will show which cell your in and how much fuel the thruster is pulling or adding which is really a multiplier that you multiply the cell by.
once your get your ve table close you can look at th fuel and spark tables and treat it like you would a carb setup, putting a/f ratio where you want it and likewise with spark.
after you mess with the datalogger you will get a feel of what cell the car operates at what engine loads like part throttle cruise, no load, etc., and you can move the spark and a/f where you want.
some of the other efi makers have better instructions if you can find and use them on setting things up.
how to tune & modify engine management systems by jeff hartman has some good info under the ems tuning 101 chapter. this has been the best book i have found although the info is still limited.
i also looked at a lot of different spark and a/f tables to get an idea of what others were doing.
http://www.megamanual.com/mtabcon.htm
i am not sure how the thruster is set up so the above info regarding the datalogger might be unuseable.
here is where i purchase my stuff, reasonable american dollars located in central u.s.
http://www.efisupply.com/store.htm
hth
i have found smoothing the ve table really does no good because the engine wants what it wants at certain points no matter what. you can smooth outside where it operates, like the cells the engine will never see. although the book i mentioned above says to string the operating cells together and smooth outside of those and you will be close.
with the datalogger you can tune in closed loop, although i have seen reference to tuning in open loop. the one time i took my car to the dyno the guy turned off closed loop to tune the ve cells.
another thing with the o2 sensor, put it in a collector if you can, but make sure there are no slip fit connections upstream, any amount of leak will throw it off i have found. also you do not want any leaks at the heads you probably know.
i had to put the sensor in a primary pipe and the reading jumps around more than a collector does.